COVID-19 Related Codes

Apr 1, 2020

This subject came up on a call I was on so here’s all the codes that I know about in various code systems that are related to COVID-19.

Note: all of these codes are subject to licensing agreements. If you want to use them - check that you have the right license.

SNOMED CT

840533007 SARS-CoV-2 organism
840536004 Antigen of SARS-CoV-2 substance
840534001 SARS-CoV-2 vaccination procedure
840535000 Antibody to SARS-CoV-2 substance
840546002 Exposure to SARS-CoV-2 event
840539006 COVID-19 disorder
840544004 Suspected COVID-19 situation

(from here, also released in an interim SNOMED CT Release 20200309, also see the summary page)

An additional code has been added into the Australian distribution of SNOMED CT:

1445431000168101 COVID-19 nucleic acid assay procedure

This is for those labs or workflows using SNOMED CT instead of LOINC.

LOINC

LOINC have a page providing context and advice which everyone using one of these LOINC codes should read.

94531-1 SARS Coronavirus 2 RNA panel – Respiratory specimen by NAA with probe detection
94532-9 SARS coronavirus+SARS-like coronavirus+SARS coronavirus 2+MERS coronavirus RNA [Presence] in Respiratory specimen by NAA with probe detection
94534-5 SARS coronavirus 2 RdRp gene [Presence] in Respiratory specimen by NAA with probe detection
94533-7 SARS coronavirus 2 N gene [Presence] in Respiratory specimen by NAA with probe detection
94499-1 Respiratory viral pathogens DNA and RNA panel – Respiratory specimen Qualitative by NAA with probe detection
94500-6 SARS coronavirus 2 RNA [Presence] in Respiratory specimen by NAA with probe detection
94502-2 SARS coronavirus+SARS-like coronavirus+SARS coronavirus 2 RNA [Presence] in Respiratory specimen by NAA with probe detection
94503-0 SARS coronavirus 2 IgG and IgM panel – Serum or Plasma Qualitative by Immunoassay
94505-5 SARS coronavirus 2 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
94506-3 SARS coronavirus 2 IgM Ab [Units/volume] in Serum or Plasma by Immunoassay
94504-8 SARS coronavirus 2 IgG and IgM panel – Serum or Plasma by Immunoassay
94508-9 SARS coronavirus 2 IgM Ab [Presence] in Serum or Plasma by Immunoassay
94509-7 SARS coronavirus 2 E gene [Cycle Threshold #] in Unspecified specimen by NAA with probe detection
94507-1 SARS coronavirus 2 IgG Ab [Presence] in Serum or Plasma by Immunoassay
94510-5 SARS coronavirus 2 N gene [Cycle Threshold #] in Unspecified specimen by NAA with probe detection
94511-3 SARS coronavirus 2 ORF1ab region [Cycle Threshold #] in Unspecified specimen by NAA with probe detection
94306-8 SARS Coronavirus 2 RNA panel – Unspecified specimen by NAA with probe detection
94307-6 SARS coronavirus 2 N gene [Presence] in Unspecified specimen by Nucleic acid amplification using primer-probe set N1
94308-4 SARS coronavirus 2 N gene [Presence] in Unspecified specimen by Nucleic acid amplification using primer-probe set N2
94309-2 SARS coronavirus 2 RNA [Presence] in Unspecified specimen by NAA with probe detection
94312-6 SARS coronavirus 2 N gene [Cycle Threshold #] in Unspecified specimen by Nucleic acid amplification using primer-probe set N2
94310-0 SARS-like Coronavirus N gene [Presence] in Unspecified specimen by NAA with probe detection
94311-8 SARS coronavirus 2 N gene [Cycle Threshold #] in Unspecified specimen by Nucleic acid amplification using primer-probe set N1
94313-4 SARS-like Coronavirus N gene [Cycle Threshold #] in Unspecified specimen by NAA with probe detection
94314-2 SARS coronavirus 2 RdRp gene [Presence] in Unspecified specimen by NAA with probe detection
94315-9 SARS coronavirus 2 E gene [Presence] in Unspecified specimen by NAA with probe detection
94316-7 SARS coronavirus 2 N gene [Presence] in Unspecified specimen by NAA with probe detection

From here. Picking between those codes requires specialist expertise on the diagnostic testing side; if you find yourself needing to pick a LOINC code for a test request code, and no specific LOINC code is specified, use the panel code 94306-8. For results without knowing which method was used, the nearest to a catch all code is 94500-6 for a respiratory specimen, or if the specimen is not known, 94309-2.

Note: where the diagnosis is based on Chest CT, one of the existing Chest CT LOINC codes would be appropriate, with one of the SNOMED CT codes above for the diagnosis.

For USA, the correct LOINC code for the “Centers for Disease Control and Prevention (CDC) 2019-Novel Coronavirus (2019-nCoV) Real-Time Reverse Transcriptase (RT)-PCR Diagnostic Panel” is 94306-8.

ICD

ICD-10 U07.1 The disease diagnosis of COVID-19
ICD-11 RA01.0 The disease diagnosis of COVID-19

From here. Note about the proper use of the ICD classifications:

Where documentation indicates acute respiratory disease due to 2019-nCoV, assign:A code for the acute respiratory condition as per the guidelines in ACS 0001 Principal diagnosis and ACS 0002 Additional diagnosesB97.2 Coronavirus as the cause of diseases classified to other chapters to identify the infectious agentU07.1 Emergency use of U07.1 as an additional diagnosis.Note: DO NOT assign U07.1 to episodes where novel coronavirus is only suspected. For suspected cases, please see ACS 0012 Suspected conditions for guidance.

See comment below from Donna for more information

For ICD-10CM in USA, see this note about which codes to use.

CPT

87635 Infectious agent detection by nucleic acid (DNA or RNA); severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Coronavirus disease [COVID-19]), amplified probe technique

Source

HCPCS

U0001 This code is used specifically for CDC testing laboratories to test patients for SARS-CoV-2
U0002 This code allows laboratories to bill for non-CDC laboratory tests for SARS-CoV-2/2019-nCoV (COVID-19) using the new, streamlined FDA policy for certain laboratories to develop their own validated COVID-19 diagnostics

Source

ICPC 2+

R83015 COVID-19
A23026 At risk;COVID-19
R29021 COVID-19;suspected
R27003 Concern (about);COVID-19
A67031 Referral;fever clinic
R33013 Test;swab;COVID-19
R45005 Advice/education;COVID-19

RxNorm

2284718 remdesivir ingredient (IN)
2284960 remdesivir 100 MG Injection Semantic Clinical Drug (SCD)

Source